РОЛЬ АТЕРОКАЛЬЦИНОЗА В РАЗВИТИИ АТЕРОТРОМБОТИЧЕСКОГО ПОДТИПА ИШЕМИЧЕСКИЙ ИНСУЛЬТ. МЕНЕДЖМЕНТ ЛЕЧЕБНОЙ ТАКТИКИ
Abstract
Objective: This review article is dedicated to analyzing the role of vascular calcification (atherocalcinosis) in the development of the atherothrombotic subtype of ischemic stroke, as well as evaluating current approaches to diagnosis, treatment, and prevention. Atherocalcinosis, as a key factor in atherothrombosis, requires in-depth study to improve clinical management of patients at high risk of stroke. Methods: A systematic analysis of scientific literature from the last five years was conducted, focusing on atherocalcinosis, its contribution to the pathogenesis of atherothrombotic stroke, and current therapeutic strategies. Particular attention was given to studies on diagnostic methods, risk factors, pharmacological therapy, surgical interventions, and prevention strategies. Results: The review revealed that atherocalcinosis promotes the progression of atherosclerotic changes and thrombus formation, increasing the risk of ischemic stroke. Modern imaging techniques (CT, MRI, ultrasound) allow accurate assessment of the extent of vascular calcification. Treatment strategies include antithrombotic agents, statins, and surgical methods such as angioplasty and carotid endarterectomy. Future therapeutic prospects involve developing molecular and genetic approaches targeting calcification inhibition. Conclusion: Atherocalcinosis is a significant risk factor for the development of atherothrombotic ischemic stroke. Current diagnostic and treatment methods provide broad opportunities for managing this condition; however, gaps remain in understanding the mechanisms of calcification and its impact on stroke outcomes. New therapeutic strategies and further research into the pathophysiology of atherocalcinosis may significantly improve clinical outcomes for patients.