ЭНДОКРИННАЯ СИСТЕМА И АТЕРОМАТОЗНЫЕ СТАДИИ АТЕРОСКЛЕРОЗА
Abstract
Relevance: Atherosclerosis is a leading cause of cardiovascular diseases, myocardial infarction, and stroke in many countries around the world. The study of pathogenetic mechanisms underlying the development of atherosclerosis is an important task for the development of effective methods for prevention and treatment. Disturbances in the functioning of the endocrine system, in particular the imbalance of adipokines (biologically active molecules produced by adipose tissue), may play a key role in the pathogenesis of atherosclerosis. Understanding the relationship between endocrine disorders and the formation of atherosclerotic plaques can contribute to the development of new approaches to the treatment and prevention of atherosclerosis. Atheromatous stages are critical in the development of atherosclerosis, as the formation and destabilization of atherosclerotic plaques are directly related to the risk of cardiovascular complications. The study of the role of the endocrine system in the processes occurring at the atheromatous stages of atherosclerosis may reveal new therapeutic targets. Thus, this direction is relevant, as it will make it possible to reveal important pathogenetic aspects of the development of atherosclerosis associated with endocrine disorders, which may contribute to the development of more effective strategies for the prevention and treatment of cardiovascular diseases.