[Morphological characteristics of cardiomyocyte death in the experimental myocardial infarction in rats with various emotional reaction].

Abstract

The peculiarities of morphological signs of cardiomyocyte death in the lesion focus in experimental myocardial infarction were studied. Infarction was induced by ligation of descending branch of the left heart coronary artery in outbred rats with 180-200 g body mass, which were previously subdivided into highly emotional (HE) and low emotional (LE) groups according to "open field" test. Microscopic study has shown that in the infarction focus of animals of both HE and LE groups cardiomyocyte death types were found that differed primarily by the state of myofibrils. Relaxation and contracture types of cardiomyocyte death were typical to HE animals, while lytic cardiomyocyte necrosis prevailed in LE group.

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