[Sex factors in effects of aerogenic toxic substances on the duration of hexenal-induced sleep].

Abstract

Inhalant poisoning with low doses of toxicants during 3 months resulted in slowing the biotransformation of hexenal in male rats, whereas lead acetate and sulphur dioxide were less active. Unlike the male rats, phenol in female ones prolonged hexenal-induced dream. Ammonia did not effect the biotransformation, whereas formaldehyde, lead acetate and sulphur dioxide accelerated it. Sex--linked dimorphism of MOS has been suggested to determine more pronounced hepatotoxicity of the compounds under exploration in male rats.

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