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Surgical treatment of postinfarction anterior left ventricular aneurysms: linear vs. patch plasty repair

Mirdavron MukaddirovV. Vakhidov Research Centre of Surgery, Tashkent, UzbekistanJ. M. FrapierbDepartment of Thoracic and Cardiovascular Surgery, CHU Arnaud de Villeneuve Hospital, 371, avenue du Doyen G. Giraud, 34295 Montpellier Cedex, FranceR. DemariaaV. Vakhidov Research Centre of Surgery, Tashkent, UzbekistanBernard AlbataV. Vakhidov Research Centre of Surgery, Tashkent, Uzbekistan
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Abstract

BACKGROUND: The patch plasty repair is increasingly advocated over linear closure in the surgical treatment of postinfarction anterior left ventricular aneurysm (LVA). A comparative estimate of the clinical results of these two techniques seemed in order. METHODS: Between 1985 and 2004, 53 patients (mean age of 64.2+/-8.3 years) underwent repair of anterior LVA. Twenty-seven patients underwent linear repair (group 1) and 26 patients patch plasty (group 2). The mean left ventricular ejection fraction was 33.9+/-8.2% in group 1 vs. 29.7+/-10.2% in group 2 (P=0.118). Preoperatively 85.2% of patients in group 1 were in NYHA functional class III or IV vs. 88.5% in group 2 (P=0.71). All patients had preoperative recurrent ventricular tachycardia (VT) and non-guided encircling cryoablation for treatment of VT was performed in all patients. Coronary revascularization was performed in 29.6% of patients in group 1 and 42.3% in group 2 (P=0.398). RESULTS: The overall in-hospital mortality was 1.9% as one patient died of low cardiac output (LCO). LCO was the most frequent early postoperative complication and was observed in 66.7% of patients in group 1 vs. 65.4% in group 2 (P=1.000). LCO was related to right coronary artery disease on multivariate analysis (odds ratio 6.9, P=0.0097). Mean follow-up was 6.4+/-4.8 years (range 1 day-17.5 years). Overall survival at 10 years was 65.5% of patients in group 1 vs. 60.6% in group 2 (P=0.395). At 10 years, 91.5% of patients were free from VT or sudden death in group 1 vs. 81% in group 2 (P=0.269). At follow-up the patients' functional status improved and among survivors 76.9% in group 1 were in NYHA functional class I-II vs. 62.5% in group 2 (P=0.432). Deaths from congestive heart failure (CHF) occurred in 38.5% of patients in group 1 vs. 55.6% in group 2 (P=0.632). On multivariate analysis a preoperative left ventricular end-diastolic pressure above 20 mmHg was a predictor of mortality from CHF (odds ratio 9.6, P=0.038). CONCLUSIONS: Our study did not reveal significant differences between linear closure and patch plasty repair in the short- and long-term. The choice of repair technique should be adapted to each patient's anatomical and physiological characteristics.

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