Article

Surface Functionalization of Biomaterials with Alkaline Phosphatase

Enrica VernéPolytechnic University of TurinSara FerrarisPolytechnic University of TurinChiara Vitale‐BrovaronePolitecnico di TorinoSilvia SprianoPolytechnic University of TurinClaudia L. Bianchi‬INFM and Università degli Studi di Milano BicoccaMarco MorraClara Cassinelli

Key engineering materialsbook series2007en

ABI

Abstract

Two different glasses, one biocompatible but with a low bioactivity index (G1) and the other with an higher bioactivity index (G2), the ceramic version of the second glass and a titanium alloy (Ti6Al4V) have been functionalizated by anchoring alkaline phosphatase (ALP) on their surfaces. The enzyme has been chosen because it is involved in mineralization processes of hard tissues and is a model for more complex ones. ALP has been grafted on glasses and glass-ceramics surfaces both with and without samples silanization and on metallic surfaces with and without tresyl chloride activation. Samples have been analyzed at each step of the functionalization process in order to verify it.

Topics

Bone Tissue Engineering Materials Dental Implant Techniques and Outcomes Dental materials and restorations

Identifiers

DOI: 10.4028/www.scientific.net/kem.361-363.593

Citations and references

Cited by 05 references

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