Article

Influence of styryl dyes on blood erythrocytes

Negmat NizomovSamarkand State University, Uzbekistan,Mubaro BarakaevaSamarkand State University, Uzbekistan,Eldar N. KurtalievSamarkand State University, Uzbekistan,Sherzod I. RahimovSamarkand State University, Uzbekistan,Dilorom P. KhakimovaGayrat KhodjayevSamarkand Agricultural Institute (Uzbekistan)V. N. YashchukKiev National Univ. (Ukraine)

Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIEjournal2008en

ABI

Abstract

It was studied the influence of F, Sbt, Sil, Sbo monomer and homodimer Dst-5, Dst-10, Dbt-5, Dbt-10, Dil-10, Dbo-10 styryl dyes on blood erythrocytes of white rats. It was shown that the homodimer styryl dyes Dst-5, Dbt-5 and Dbo-10 decrease the erythrocytes quantity by 1.5-2 times more as compared with monomer dyes Sbt and Sbo. The main cause of dyes different action is the different oxidation degree of intracellular hemoglobin evoked by these dyes. It was established that the observed effects was connected with different penetration of these dyes through membrane of erythrocytes and with interaction of these dyes with albumin localized in membranes of cells.

Topics

Chemical and Physical Studies Optical Imaging and Spectroscopy Techniques

Identifiers

DOI: 10.1117/12.793955

Citations and references

Cited by 05 references

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