Article

Ethyl 3,3,3-trifluoro-2-hydroxy-2-(5-methoxy-1<i>H</i>-indol-3-yl)propionate

Zukhra C. KadirovaTashkent Chemical–Technological Institute, Navoi St. 32, Tashkent 100011, UzbekistanSamat TolipovOleg FedorovskiyA.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Vavilova St. 28, Moscow 119991, Russian FederationIbragimov BakhtiyarN.A. ParpievNational University of Uzbekistan named by Mirzo Ulugbek, Chemical Faculty, Vuzgorodok, Tashkent 100123, Uzbekistan

Acta Crystallographica Section E Structure Reports Onlinejournal2011en

ABI

Abstract

In the title compound, C(14)H(14)F(3)NO(4), the 3,3,3-trifluoro-pyruvate fragment has a syn configuration and is noncoplanar with the indole plane [dihedral angle = 84.87 (5)°]. In the crystal, mol-ecules form inversion-related dimers via pairs of inter-molecular O-H⋯O hydrogen bonds. These dimers are connected by inter-molecular N-H⋯O=C(CF(3)) hydrogen bonds to form a two-dimensional network structure.

Topics

Fluorine in Organic Chemistry Synthesis and Reactions of Organic Compounds Synthesis and Biological Evaluation

Identifiers

DOI: 10.1107/s1600536811021489

Citations and references

Cited by 06 references

Metrics — AkademScholar