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Diversity of gossypol clathrates with pyrazine

M. HonkeldiyevaInstitute of Bioorganic Chemistry, Tashkent, Uzbekistan,S. A. TalipovInstitute of Bioorganic Chemistry, Tashkent, Uzbekistan,Б. Т. ИбрагимовInstitute of Bioorganic Chemistry, Tashkent, Uzbekistan,J. HulligerUniversity of Berne, Freiestrasse 3, CH-3012, Berne, (Switzerland)
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Abstract

antiaggregating drug reveals that phase relationships should be investigated. Knowing the solid state properties of ticlopidine hydrochloride polymorphs would avoid unexpected bioavailability resulted from solubility and stability changes. Since ticlopidine hydrochloride is not well studied in terms of solid state structures and properties, this study means an advance in its characterization and understanding of conformational features and crystal packing patterns.

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