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ABSTRACT 238

Shamir GellerPediatrics, Tashkent Medical Pediatric Institute, Tashkent, Uzbekistan
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Abstract

Background and aims: Food allergy is a hypersensitivity to the food based on immune mechanisms. In infants the disease often manifests as the lesions of the gastrointestinal tract. The basis of treatment is an elimination food-cause significant allergen. Aims: To determine the clinical - prognostic value of using the elimination diets in the food allergy treatment in children. Methods: We examined 25 children with a diagnosis ‘food allergy, gastrointestinal form’ aged from 0 to 5 years, who were hospitalized at the Department of Gastroenterology. Verification of the diagnosis was carried out considering anamnesis, clinical, laboratory methods of examination. Research agreed with IRB. Results: In most children the disease was accompanied by symptoms of gastroesophageal reflux, vomiting, loose stools with an admixture of large amounts of mucus and even blood. Cow’s milk protein were playing leading role in the defeat of the gastrointestinal tract in children. These products have been excluded from the diet of patients. Children were fed hypoallergenic mixtures based on goat milk. It has been found that the goat milk is better digested and absorbed in the gastro-intestinal tract of infants than cow’s. For better digestion and splitting of food allergens the number of meals has increased while reducing their single volume. The research found that the use of this diet gives positive results after 3–4 days. So, 85% of children showed improvement in general condition, the disappearance of symptoms. Conclusions: Transfer the patient to a hypoallergenic diet helps improve the state, it is the prevention of complications, such as ulcerative colitis, sensitization to other allergens, occurrence of combined organ pathology.

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