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Biomarkers of Liver in Patients with Chronic Pancreatitis Associated with Metabolic Syndrome

Gulchehra R. YuldashevaTashkent Institute of Postgraduate Medical Education;Tashkent, UzbekistanF. I. KhamrabaevaTashkent Institute of Postgraduate Medical Education;Tashkent, UzbekistanA. A. KhadzhimetovTashkent Medical Academy; Tashkent, Uzbekistan
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Abstract

A study of the carbohydrate and lipid metabolism, as well as the leptin level was conducted in 69 patients with chronic pancreatitis (CP) associated with the metabolic syndrome (MS). The results revealed significant changes in the serum parameters studied in patients with CP and MS. The authors concluded that in such patients, the irregularities in the glucose-insulin homeostasis are evident, not only due to hormonal disorders, but also due to impairment cellular metabolism, against the backdrop of excessive free fatty acid (FFA) levels.

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