EXTERNAL EVALUATION OF THE QUALITY OF CLINICAL AND DIAGNOSTIC LABORATORIES. POSSIBLE SOURCES OF ERRORS
Abstract
The purpose of this study was to assess the quality of laboratory research, its problem areas and potential improvements using the example of a number of regional clinical diagnostic laboratories in the Tashkent region and the comparability of laboratory analysis data obtained in various laboratories. We have evaluated the quality of laboratory tests in 40 clinical diagnostic laboratories of the Tashkent region. The control was carried out on 9 biochemical parameters of blood. In our studies using the control serum, the results were deplorable: the error was 50% in determining the OB and glucose, and the correct results were obtained in only 30% of the laboratories; biliru-bin - unreliable results were issued in 40% of laboratories, ALT - in 45%, and creatinin in 60%. Moreover, the results were issued in different units. The coefficient of variation (CV) was used to assess the convergence, reproducibility and accuracy of measurements of laboratory parameters in the control material and patient samples. The results of the study showed that its value exceeded the recommended maximum permissible coefficient of variation when measuring concentration levels for more than half of the studied components.