FEATURES OF THE COMORBID FLOW OF UNSTABLE STENOCARDIA AND THE ANXIETY-DEPRESSIVE SYNDROME DEPENDING ON THE BLOOD CYTOKINE LEVEL
Abstract
195 patients (102 men and 93 women) aged from 35 to 75 years (mean age 62.57 ± 0.75 years) suffering from unstable forms of IHD were examined on the basis of the SB RSCEMA in the emergency and cardiac resuscitation departments. All patients were tested using the Hospital Anxiety and Depression Scale. Based on the psychopathological examination data, all patients were divided into 2 groups. The first group included 109 patients with unstable angina with clinically significant affective disorders, which amounted to 55.89%. The second − the comparison group - 86 (44.1%) patients with unstable angina without affective disorders. Studies have shown that when comparing inflammatory markers − cytokines in patients with unstable angina, the pro-inflammatory cytokines IL-1 and TNFα are increased in individuals with comorbid pathology, depending on the presence or absence of affective disorders of the anxiety-depressive spectrum.