The impact of pulse currents on morphological changes in lung and heart tissue underchronic purulent pneumonia
Abstract
We examined outbred rats with a model of chronic purulent pneumonia. We detected the damages to the interstitial tissue with the development of granulations and foci of inflammation, pneumosclerosis in the lung tissue. Uneven hypertrophy of cardiomyocytes, thickening of the walls of blood vessels and an increase in their quantitative ratio, moderate proliferation of connective tissue layers in the perivascular zones, intermuscular edema with impaired circulation of the muscle wall were manifested in the heart tissue. After electrical myostimulation pulse currents of the respiratory muscles in the lung tissue revealed increased amount of connective tissue in the septa, increase in the number of macrophages, and in cardiac tissue focal dissociation of cardiomyocytes, irregular interstitial edema, hypertrophy of the walls of arterioles, hyperemia, poor circulation in the appearance of focal hemorrhages in the myocardium and epicardium.