Organ-on-a-chip: the next generation platform for risk assessment of radiobiology
Yi QuanChinaMiao SunChinaZhaoyi TanChinaJan C. T. EijkelBIOS, Lab on a Chip GroupAlbert van den BergBIOS, Lab on a Chip GroupAndries D. van der MeerDepartment of Applied Stem Cell TechnologiesYanbo XieChina
ABI
Abstract
. In this paper, we briefly reviewed the state-of-the-art in organ-on-a-chip research in different domains, and conclude with the challenges of radiobiology studies at internal low-dose irradiation. Organ-on-a-chip technology has the potential to significantly improve the radiobiology study as it can mimic the function of human organs or tissues, and here we summarize its potential benefits and possible breakthrough areas, as well as its limitations in internal low-dose radiation studies.
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