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Rapid <sup>18</sup>F-labeling <i>via</i> Pd-catalyzed <i>S</i>-arylation in aqueous medium

Swen HumpertForschungszentrum Jülich GmbHMohamed Aymen OmraneForschungszentrum Jülich GmbHElizaveta A. UrusovaForschungszentrum Jülich GmbHLothar GremerForschungszentrum JülichDieter WillboldGermanyHeike EndepolsForschungszentrum Jülich GmbHР. Н. КрасиковаN. P. Bechtereva Institute of the Human BrainBernd NeumaierForschungszentrum Jülich GmbHBoris D. ZlatopolskiyForschungszentrum Jülich GmbH
Chemical Communicationsjournal2021en
ABI

Abstract

F]fluoro-5-iodopyridine, which is readily accessible using the "minimalist" radiofluorination method. The practicality of the procedure was confirmed by preparation of a novel PSMA-specific PET-tracer as well as labeling of glutathione, Aβ oligomer-binding RD2 peptide, bovine serum albumin and PSMA I&S.

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