Article

Withanolides from <i>Physalis angulata</i> L.

R. Ya. OkmanovS.Yunusov Institute of the Chemistry of Plant Substances Academy of Sciences, of Uzbekistan 100170, Mirzo Ulugbek Str., 77, Tashkent, UzbekistanM. M. MakhmudovaS.Yunusov Institute of the Chemistry of Plant Substances Academy of Sciences, of Uzbekistan 100170, Mirzo Ulugbek Str., 77, Tashkent, UzbekistanI. D. BobaevS.Yunusov Institute of the Chemistry of Plant Substances Academy of Sciences, of Uzbekistan 100170, Mirzo Ulugbek Str., 77, Tashkent, UzbekistanB. TashkhodjaevS.Yunusov Institute of the Chemistry of Plant Substances Academy of Sciences, of Uzbekistan 100170, Mirzo Ulugbek Str., 77, Tashkent, Uzbekistan

Acta Crystallographica Section E Crystallographic Communicationsjournal2021en

ABI

Abstract

The compounds (17 S ,20 R ,22 R ,24 R ,25 S )-5β,6β:20,24-diepoxy-4β,25-dihydroxy-1-oxowith-2-en-26,22-olide and (20 R ,22 R )-5α,14α,20-Trihydroxy-1-oxo-6α,7α-epoxywitha-2-enolide were isolated from a chloroform extract of the aerial parts of Physalis angulata L. (Solanaceae). Two products were isolated from the chromatographic separation extract. Compound I corresponds to physangulide B chloroform monosolvate, C 28 H 38 O 7 ·CHCl 3 , while compound II is 14α-hydroxyixocarpanolide, C 28 H 40 O 7 . In the two molecular structures, the conformation of the steroid part (rings A , B , C , D ) does not differ. In both crystals, molecules are linked by intermolecular O—H...O hydrogen bonds along the c- axis direction and form a two-dimensional network parallel to the ac plane. The absolute configuration was determined from X-ray diffraction data.

Topics

Phytochemicals and Medicinal Plants Pharmacological Effects of Medicinal Plants Essential Oils and Antimicrobial Activity

Identifiers

DOI: 10.1107/s205698902100709x

Citations and references

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