Epidemiology of kidney cancer in Uzbekistan
Abstract
Kidney carcinomas that primarily affect adults include malignant tumors that emerge from kidney parenchyma and kidney pelvis. Almost all the malignant tumors arising from the renal pelvis are classified as transitional cell carcinomas, while less than 10% of them are considered to be microscopically verified renal carcinomas.\n\n Since adenocarcinomas occur mainly from the renal parenchyma the name of this disease is renal cell carcinoma and it constitutes more than 90% of kidney carcinomas. Most cases of kidney cancer in children are nephroblastomas (Wilms' tumor), accounting for about 1.1% of all cases of kidney cancer, but this pathology is not the focus of the current review.\n\n The histological type of the majority of renal cell carcinomas are the clear cell type, followed by papillary and chromophobic types. Although histological subtypes of renal cell carcinoma may differ in clinical characteristics and genetic determinants, epidemiological data on the renal cell carcinoma subtype in Uzbekistan are insufficient to reveal consistent patterns.