Evaluation of the effect of a new drug on morphological changes in burn shock
Abstract
Abstract. The study of various aspects of burn shock and the development of new methods of treatment still remain relevant, this is due to the high rates of lethal outcomes, which largely depend on such factors as the area of thermal burns, the depth of injury, as well as the time elapsed from the onset of thermal trauma to the provision of specialized care[9]. It is known that high mortality occurs in burns with lesions of the body surface of 40-50% and supercritical deep burns exceeding 50% of the body surface area [1,5]. An important condition for improving the results of treatment of patients with thermal trauma is the use of more effective methods of treatment, including infusion therapy [4]. For this purpose, we used in the experiment a new infusion blood substitute "Reoambrasol", which has antioxidant, antihypoxic and detoxifying effects [6,7].