ATOPIC DERMATITIS AND METHODS OF ITS TREATMENT
Narzikulov R.M.PhD of the Department of Skin and Venereal Diseases of Samarkand Medical UniversityUrinov F.K.Samarkand Medical UniversityXamraeva D.I.Samarkand Medical University
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Abstract
Introduction: Atopic dermatitis (syn.: atopic eczema, constitutional eczema, diffuse neurodermatitis) is a chronic relapsing skin disease that manifests itself in adult patients with erythematous-papular rashes with lichenization phenomena, accompanied by constant, often painful, itching and developing in the presence of a genetic predisposition to hyperactive the state of the Th2-helper system and the filagrin-dependent defect in the barrier function of the skin. According to numerous epidemiological studies, AD affects about 5% of the world's population, and in the age group of early childhood, the severity of atopic skin lesions is diagnosed in almost 30–50% of cases.
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