IDENTIFICATION OF ЕARLY DISORDERS OF GLOMERULAR FILTRATION RATE DEPENDING ON THE DEGREE OF OBESITY
Abstract
Obesity increases the risk of developing a number of comorbid diseases, including cardiovascular disease, chronic kidney disease, diabetes mellitus, arterial hypertension, and metabolic syndrome. Obesity is well known as an independent risk factor for chronic disease. The glomerular filtration rate (GFR) is the best routine measure of kidney function available and is essential for monitoring and managing both acute kidney injury (AKI) and chronic kidney disease (CKD). Creatinine is the most commonly used GFR biomarker. Creatinine levels may be influenced by factors unrelated to detection such as gender, muscle mass, ethnicity, and dietary factors. Cystatin is an alternative biomarker for evaluating GFR that is independent of muscle mass, age, and gender.