OXIDATIVE DEGRADATION OF LIPID AND THE ROLE OF ANTIOXIDANTS IN CARCINOGENESIS
Abstract
Abstract: This article will consider the role of "Oxidative lipid degradation". This process is a physiological process that takes part in the regulation of cellular functions. The processes of free radical oxidation of lipids and proteins are one of the important regulatory mechanisms for the assimilation of carbohydrates, proteins, lipids, nucleic acids, which underlies the plastic and energy supply of the functions of the cell and the body as a whole.\n\n\nWith an increase in the level of free radical oxidation, lightning-fast destruction of cellular structures occurs as a result of their damage.\n\n\nIt is well known that pathological changes in the body lead to an increase in the level of lipid peroxidation. At the same time, in the body, as a result of chemical transformations, the formation of certain substances occurs, which, for one reason or another, have not been oxidized or not completely restored. These substances, consisting of special groups of atoms or molecules, have a very high reactivity, since they contain unpaired electrons in the outer electronic levels and are called "free radicals".\n\n\nUntil now, there is no complete understanding of the nature of the restructuring of peroxidation processes in malignant pathology, and the obvious staging of changes in the lipid peroxidation system in the dynamics of carcinogenesis creates certain difficulties for the effective use of antioxidants as antitumor agents.