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STUDY OF THE MORPHOMETRIC INDICATORS OF THE LIVER OF PUREBRED RATS UNDER THE INFLUENCE OF 4 TYPES OF ANTI-INFLAMMATORY DRUGS IN POLYPHARMACY

USANOV Sanjar SadinovichDoctor of Medical Sciences, Associate Professor Samarkand State Medical UniversityISMOILOV Ortik IsmoilovichDoctor of Medical Sciences, Associate Professor Samarkand State Medical University
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Abstract

Objective: The main purpose of the work was to study the cellular composition of the rat liver in laboratory conditions are in polypharmacy. Methods:If we take into account the development of the field of pharmacology, it is common for sick people to take many drugs at the same time. Results: This, in turn, leads to a malfunction of the liver, which is a large laboratory in the human body. The negative consequences of taking many drugs at the same time is called polypharmacy and is currently one of the developing problems. The term "polypragmasia" is often used in the medical literature, but there is no generally accepted definition. Conclusions. For this purpose, the parameters of comparison of the morphometric parameters of the liver of purebred rats under the influence of 4 different anti-inflammatory drugs in normal conditions and in polypharmacy were studied. The purpose of the work was to study and complete microscopic data on morphological and morphometric parameters of liver tissue.

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