Article

ENDOTHELIAL DYSFUNCTION AND CYTOKINES: A ROLE IN THE DEVELOPMENT OF PREMATURE DEPARTMENT OF A NORMALLY LOCATED PLACENTA

Komilova Mastura SafarovnaTashkent State Dental Institute Tashkent, UzbekistanPakhomova Zhanna EvgenievnaCity maternity complex №6 Tashkent, Uzbekistan

Zenodo (CERN European Organization for Nuclear Research)repository2022en

ABI

Abstract

For the normal development and functioning of the placenta, it is important to have a balance between various mechanisms of angiogenesis, as well as a balance between the processes of angiogenesis and apoptosis, which is maintained by the ratio of proangiogenic and antiangiogenic factors secreted by both the endothelial cells themselves and the cells of the microenvironment. Changes in the balance of cytokines and vascular growth factors in the microenvironment of endothelial cells underlie pathological disorders of placentation, gestation at different stages of pregnancy, and preterm birth.

Topics

Pregnancy and preeclampsia studies Reproductive System and Pregnancy Preterm Birth and Chorioamnionitis

Identifiers

DOI: 10.5281/zenodo.7418824

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