Neuropeptides as Markers of Brain Damage
Abstract
Research on biomarkers for diagnosing various brain lesions has been ongoing for more than 25 years, but at present, the ideal biomarker has not been found.Among biochemical markers, the determination of the level of neurospecific proteins is being actively studied.Given the large number of neuropeptides that are currently being studied, the purpose of our work is to consider only some of them, which, in our opinion, are of greatest interest.It is protein S100, neuron-specific enolase , myelin basic protein, brain-derived neurotrophic factor.They are being actively studied to identify, determine the prognosis and severity of strokes [1; 2], traumatic brain injury (TBI) [3-5], chronic cerebral ischemia (CCI) [6], brain tumors [7], cognitive impairment in diabetes mellitus [8], cognitive impairment in neurodegenerative diseases [9 ], epilepsy [10], perinatal lesions of the nervous system [11; 12], including for postoperative cerebral complications [13; 14, 15].