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Chronic Heart Failure and Progressive Angina

Dilbar Baxridinovna RakhmatovaAssociate professor, PhD. Assistant, Bukhara State Medical Institute (Uzbekistan)Olim Nutfullaevich KhusenovAssistant, Bukhara State Medical Institute (Uzbekistan)Alisher SolievAssistant, PhD. Bukhara State Medical Institute (Uzbekistan)Nigora Sadullaevna NurovaAssistant, PhD. Bukhara State Medical Institute (Uzbekistan)
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Abstract

Chronic heart failure (CHF) is a “pathophysiological syndrome in which, as a result of a particular disease of the cardiovascular system or under the influence of other etiological causes, the heart’s ability to fill or empty is impaired, accompanied by an imbalance of the neurohumoral systems (RAAS, sympathoadrenal system, natriuretic peptides, kallikrein-kinin system). As well as the development of vasoconstriction and fluid retention, there is a dysfunction of the heart (remodeling) and other target organs (proliferation), as well as a discrepancy between the provision of organs and tissues of the body with blood and oxygen with their metabolic needs” [1-3].

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