Analysis of the results of the study on the determination of cytokines in patients with chronic hepatitis c depending on the presence of crioglobulinemia
Abdurashid OblokulovBukhara State Medical Institute named after Abu Ali ibn Sino, Bukhara, UzbekistanMukhriddin AbdulloevBukhara State Medical Institute named after Abu Ali ibn Sino, Bukhara, UzbekistanAziza JalilovaBukhara State Medical Institute named after Abu Ali ibn Sino, Bukhara, Uzbekistan
ABI
Abstract
40 patients with CHC with extrahepatic manifestations were involved in the conducted studies to determine the cytokines IL-10 and IL- 18 in patients with CHC, depending on the presence of cryglobulinemia. The results of the study showed that in patients with chronic hepatitis C with extrahepatic manifestations, the anti-inflammatory cytokine IL-10 was reduced by 2.37 times in patients, and there was a significant increase in the content of pro-inflammatory cytokine IL-18 in the blood serum by 2.71 times in relation to normal values.
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