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COMPARATIVE ANALYSIS OF INDIVIDUAL REPRESENTATIVES OF THE MICROBIOTA OF THE PERIIMPLANT ZONE IN NORMAL AND INFLAMMATORY CONDITIONS

M. EbrakhimDepartment of Orthopedic Dentistry, Tver State Medical University, Tver, RussiaValery StrelnikovProfessor of the Department of Orthopedic Dentistry, Tver State Medical University, Tver, RussiaYu. V. ChervinetsProfessor, Head of the Department of Microbiology and Virology with a course in immunology, Tver State Medical University, Tver, Russia,Д.А. МоисеевHead of the Laboratory of Simulation Technologies in Dentistry, Associate Professor of the Department of Therapeutic Dentistry, Pirogov Russian National Research Medical University, Moscow, Russia,Alaa SalloumDepartment of Surgical Dentistry and Maxillofacial Surgery, Tver State Medical University, Tver, RussiaAurelia LeontevaDepartment of Microbiology and Virology with a course in Immunology, Tver State Medical University, Tver, Russia,D. I. TaylakovaAssociate Professor of the Department of Therapeutic Dentistry, Bukhara State Medical Institute named after Abu Ali ibn Sino, Bukhara, Uzbekistan,Barno MuydinovaTherapeutic Stomatology Department, Andijan State Medical Institute, Andijan, Uzbekistan,L A Gusdentist-therapist at the Department of Therapeutic and Preventive Dentistry, Central Research Institute of Stomatology and Maxillofacial Surgery, Moscow, RussiaYu.L. Vasil’evProfessor, Department of Operative Surgery and Topographic Anatomy, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia,
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Abstract

Background:The incidence of periimplantitis has increased significantly in recent years, which has led to an increase in the number of implant rejection cases and a deterioration in patients' lives. The purpose of the study. To conduct a comparative analysis of individual representatives of the microbiota of the peri-implant sulcus in normal and inflammatory conditions. Materials and methods: Samples of the contents of the peri-implant sulcus from 20 patients with healthy peri-implant tissues and 20 patients with peri-implantation. The quantitative and qualitative composition of the microbiota in the samples was determined by the classical bacteriological method. Results:It was found that Streptococcus spp., Staphylococcus spp., Candida spp. and Escherichia coli predominate in the samples obtained from patients of the main group. Moreover, the number of Candida spp. In the main group, the number of Candida spp is 20.8 times higher. in the comparison group. In addition, representatives of Sarcina spp., which had not previously been associated with the development of peri-implantitis, were found. Conclusion:The microbiota plays a crucial role in the development of peri-implantitis. Further research aimed at understanding the role of various microorganisms and their mechanisms of action will make it possible to develop effective strategies for the prevention and treatment of this complex disease. Maintaining good oral hygiene and regular routine checkups remain key factors in preventing the development of peri-implantitis.

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