Characteristics of Morphometric Indicators of The Kidneys in Gestancial Pyelonephritis According to Pregnancy Parity
Abstract
Basically, the morphometric parameters of the cells and fibrous structures of the kidney in the morphofunctionally actively stained areas were taken as the basis for expressing the trajectory of the values measured during the morphometry process within a certain range by numbers. The specific features of the morphometric parameters of the parenchymal and mesenchymal structures of the kidneys of 40 women who died from gestational pyelonephritis, who underwent autopsy at the Republican pathologoanatomical center of Uzbekistan, were studied using the Hamamatsu (QuPath-0.4.0, NanoZoomer Digital Pathology Image) morphometric software. To determine the morphometric parameters, the location, size, area occupied, size of cells, width of blood vessels, diameter, perimeter, volume of lumens in a given volume and other indicators were obtained. In the study, the superiority of all morphofunctional parameters over the control group was up to 1.35 times in the I-pregnancy, up to 1.2 times in the II-pregnancy, which was explained by the weakness of morphological adaptation mechanisms, a decrease in the age-related reactivity of vascular components.