The Role Of Nutritional Support In Pediatrics For Hereditary And Multifactorial Connective Tissue Disorders
Abstract
Connective tissue disorders (CTDs) in children represent a heterogeneous group of hereditary and multifactorial diseases that primarily affect the structural integrity and function of collagen, elastin, and the extracellular matrix. These disorders often result in musculoskeletal deformities, vascular fragility, and systemic complications. Nutritional support has emerged as a crucial adjunctive therapy in managing CTDs by enhancing tissue repair, modulating inflammation, and improving overall growth and development. This study reviews current evidence on the role of nutrients—such as proteins, vitamins, minerals, and fatty acids—in the management of pediatric connective tissue disorders, emphasizing the importance of individualized nutritional strategies in improving clinical outcomes and quality of life.