CLINICAL AND LABORATORY ASSESSMENT OF RENAL DYSFUNCTION IN LIVER CIRRHOSIS
Anagul, SamadovaAssistant at Urgench Branch of Tashkent Medical Academy, department of internal disease at regional hospital of Khorezm region, Urgench, Uzbekistan
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Abstract
The study investigated the significance of clinical and laboratory parameters and cystatin C levels in assessing renal dysfunction in patients with liver cirrhosis. A total of 90 patients and 30 healthy controls were examined. Patients with renal dysfunction showed significantly increased creatinine, urea, and cystatin C levels, with a decreased glomerular filtration rate (p<0.05). Cystatin C demonstrated a negative correlation with GFR and a positive correlation with creatinine and urea. The findings suggest that cystatin C may serve as an additional marker for early detection and prognostic evaluation of hepatorenal syndrome.
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