MODIFIED METHOD OF FREEZING SUBCULTURED CELL LINES
Khamidova U.BS.Yu . Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of UzbekistanTerenteva E.OS.Yu . Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of UzbekistanUmarova M.RS.Yu . Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
Zenodo (CERN European Organization for Nuclear Research)repository2025
ABI
Abstract
Long-term storage of cell lines is a crucial component of modern cell biology, oncology, and biomedical research. Continuous passaging of cells increases the risk of genetic drift, phenotypic alterations, and contamination. Cryopreservation reduces these risks by maintaining cells in a metabolically inactive state. In addition, cryopreservation ensures genetic stability, experimental reproducibility, and continuity of cell-based studies.
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