Immunoenzymatic alterations in the context of systemic inflammation in patients with silicosis

Abstract

Harmful occupational factors in the mining industry are independent risk factors for the development of pulmonary pathology. It was found that drillers (tunnelers) are most frequently affected, with an average age of 41.6±1.2 years and work experience of up to 10 years. As the severity of silicosis increases, the level of systemic inflammatory factors (SIF) also rises. The presence of second- and third-stage silicosis and elevated SIF levels made it possible to reliably predict the likelihood of developing occupationnally induced pulmonary pathology.

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DOI

10.65491/1727-9712-2025-3-41-51

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