Clinical AND Pathogenetic Features OF Hyperprolactinemia AND Anovulatory Dysfunction in Women with Hypothyroidism
Abstract
This article investigates the clinical and pathogenetic characteristics of hyperprolactinemia and anovulatory dysfunction in women with insufficient thyroid function. Insufficient thyroid function leads to increased prolactin secretion, which disrupts the normal hormonal regulation of the ovaries, resulting in menstrual irregularities, ovulation failure, and infertility. The study analyzes epidemiological data, pathophysiological mechanisms, clinical manifestations, diagnostic approaches, and treatment strategies. Early detection and appropriate hormonal therapy, including thyroid hormone replacement and prolactin-lowering interventions, are essential to restore reproductive function. Understanding these interactions is critical for improving fertility outcomes and providing evidence-based management for affected women.