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Synthesis and structural elucidation of a trifluoromethylated cyclopentene hydrazone: a combined X-ray and computational study

Elizaveta V. PanovaUniversity of Tyumen, Tyumen, 625003, Russian FederationBakhtiyor Sh. GanievBukhara State University, M. Ikbol str., 11, 200117, Bukhara, UzbekistanKuvondik G AvezovBukhara State University, M. Ikbol str., 11, 200117, Bukhara, UzbekistanBako B. UmarovBukhara State University, M. Ikbol str., 11, 200117, Bukhara, UzbekistanJulia Konstantinovna VoroninaN.S. Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences, Leninsky prosp. 31, 119991 GSP-1, Moscow, Russian FederationDamir A. SafinDepartment of Chemistry, Dogus University, Dudullu-Ümraniye, 34775 Istanbul, Turkey
New Journal of Chemistryjournal2026en
ABI

Abstract

We report on benzoylhydrazo-2-trifluoroacetylcyclopent-1-ene ( 1 ), which structural and electronic properties were studied, and a prediction was made regarding its potential activity against hemoglobin S, which is a key protein in sickle cell anemia.

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