MORPHOMETRIC CHARACTERISTICS OF THE RAT NEPHRON IN NORMAL CONDITIONS AND DURING CORRECTION AGAINST THE BACKGROUND OF CHRONIC RADIATION SICKNESS
Abstract
Resume. In the experiment on rats, a comparison was made of the morphological changes in parts of rat kidney nephron normal and under the influence of ASD fraction 2 against the background of chronic radiation sickness. To establish the dynamics of changes in morphometric parameters of the area of the renal corpuscle, proximal and distal convoluted tubules of the kidneys of 6-month-old rats in normal conditions and under the influence of ASD fraction 2 against the background of chronic radiation sickness. The effect of tissue drug ASD-2 as correctors can be explained by the fact that this drug reduces the production of free oxygen radicals, which have damaging effects on biological membranes of cells, proteins, nuclear chromatin, and also disrupt the stability of ion channels and receptors. Key words: nephron, proximal convoluted tubule, distal convoluted tubule, chronic radiation sickness, ASD-f2.