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STUDY OF THE BENZYLATION REACTIONS OF 6-AMINOPURINE AND ITS IMMOBILIZATION PROPERTIES IN HYDROGEL CAPSULES

Ozoda Kamolova1Samarkand State Pedagogical InstituteGayrat HaydarovSamarkand State Pedagogical InstituteFoziljon Saitkulov2Tashkent state agrarian university3Qosim Zakhidov3Samarkand State university
Open MINDrepository2026en
ABI

Abstract

6-Aminopurine is an important heterocyclic compound exhibiting pronounced biological activity and serving as a precursor of plant growth regulators and coordination ligands. In this study, the benzylation reactions of 6-aminopurine were investigated under various reaction conditions in order to obtain selectively substituted derivatives. The influence of solvent polarity, base strength, temperature, and reagent ratio on the direction of N-alkylation was analyzed, with particular attention to substitution at the N7 and N9 positions of the purine ring. The synthesized benzylated products were isolated and structurally characterized using FT-IR, UV–Vis and NMR spectroscopy, confirming successful modification of the heterocyclic system.

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