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ANATOMICAL DEVELOPMENTAL FEATURES OF OFFSPRING KIDNEYS UNDER THE INFLUENCE OF CHRONIC MATERNAL INTOXICATION.

Zulfiya Choriyevaenior Lecturer of the Department of Anatomy and Clinical Anatomy, Candidate of Medical Sciences (PhD)Og'abek Pardayev1st year undergraduate students of TSMU Termez branch
Open MINDrepository2026
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Abstract

This article examines the anatomical developmental features of the offspring’s kidneys under the influence of chronic maternal intoxication. Prolonged exposure of the maternal organism to toxic factors during pregnancy may adversely affect the formation and differentiation of fetal organs, particularly the kidneys. The study analyzes both macroanatomical and microanatomical parameters of the offspring’s kidneys, including kidney size and weight, the ratio of cortical and medullary layers, the degree of nephron development, and the structural characteristics of tissue components. The findings indicate that under conditions of chronic maternal intoxication, delayed anatomical development, structural alterations, and decreased morphometric parameters may be observed in the offspring’s kidneys. The results of this study are important for assessing the impact of harmful prenatal factors and for the early detection of anatomical changes in renal development.

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