Acute Pancreatitis And Cationic Trypsinogen Gene Polymorphism In The Uzbek Population
Ismailov Uktam SafaevichDepartment of Surgical Diseases No. 1, Tashkent State Medical University, UzbekistanMadatov Kurbonboy AminboevichDepartment of Surgical Diseases No. 1, Tashkent State Medical University, UzbekistanMatmuratov Seyilkhon KuronboevichDepartment of Surgical Diseases No. 1, Tashkent State Medical University, UzbekistanSharopov Asliddin NasriddinovichDepartment of Surgical Diseases No. 1, Tashkent State Medical University, UzbekistanRakhimov Rasulbek IbrokhimovichDepartment of Surgical Diseases No. 1, Tashkent State Medical University, Uzbekistan
ABI
Abstract
This article examines the impact of the Arg122His polymorphism in the PRSS1 gene on the incidence of acute pancreatitis. In the mechanism of acute pancreatitis development, environmental factors play an important role alongside genetic factors. Ethnic differences in the frequency distribution of alleles and genotypes of this gene's polymorphic variant were identified. Further advancement of molecular genetic research through studying the genetic basis of pancreatitis is crucial for developing new diagnostic methods and determining treatment strategies with an individualized approach to each patient.
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