HORMONAL AND GENETIC MECHANISMS OF METABOLIC-ASSOCIATED STEATOTIC LIVER DISEASE IN WOMEN OF REPRODUCTIVE AGE
Dilfuza YunusovaAssistant, Department of Normal Physiology, Andijan State Medical InstituteJ. B. RavzatovPhD, Associate Professor, Department of Family Medicine Training, Andijan State Medical Institute
Zenodo (CERN European Organization for Nuclear Research)repository2026
ABI
Abstract
Metabolic-associated steatotic liver disease is currently one of the most pressing issues in hepatology and metabolic medicine. In addition to insulin resistance, obesity, dyslipidemia, and chronic low-grade inflammation, hormonal imbalance and genetic factors also play a significant role in the development of this disease. In particular, in women of reproductive age, special importance is attributed to estrogens, androgens, sex hormone-binding globulin, the aromatase system, as well as genes associated with steroid metabolism.
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