MODELING THE ROLE OF HORMONAL DYNAMICS AND ANTI-HORMONAL THERAPIES IN BREAST CANCER: A MULTIMODAL COMPUTATIONAL FRAMEWORK
Dr Saloni JainAssistant Teacher, Samarkand State Medical University, UzbekistanAyush SharmaMedical Student, Samarkand state Medical University, UzbekistanSusheen BhatMedical Student, Samarkand state medical university, UzbekistanPurvanshaMedical Student, Samarkand State Medical University, Uzbekistan
ABI
Abstract
Breast cancer remains the most prevalent malignancy among women globally, with endocrine therapy representing the cornerstone of treatment for hormone receptor-positive subtypes. However, the emergence of therapeutic resistance poses significant clinical challenges. This narrative review presents a comprehensive computational framework integrating mathematical modeling, systems biology, and clinical pharmacology to understand hormonal dynamics in breast cancer progression and treatment response.
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