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Development of an Analytical Method for Mephedrone and Methamphetamine Using Gas Chromatography-Mass Spectrometry (GC-MS)

Abdukhalikova Nargiza UktamovnaTashkent Pharmaceutical Institute, Tashkent, Republic of UzbekistanYuldashev Zakirdjan AbidovichTashkent Pharmaceutical Institute, Tashkent, Republic of UzbekistanZulfikarieva Dilnoza AlisherovnaTashkent Pharmaceutical Institute, Tashkent, Republic of UzbekistanNurmatova Malohat IsmatovnaTashkent Pharmaceutical Institute, Tashkent, Republic of Uzbekistan
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Abstract

This article presents the properties of synthetic psychostimulants mephedrone and methamphetamine as well as the results of developing gas chromatography–mass spectrometry (GC-MS) methods for their identification from biological matrices. In the study, substances extracted from biological samples such as blood, urine, and liver were identified using standard reference materials. For each substance, the characteristic retention time and mass of ion fragments were determined. It was established that the developed method offers high accuracy and sensitivity.

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