The Effect of the Fixed-Dose Combination of Telmisartan/Amlodipine on the Regression of Left Ventricular Hypertrophy and Arterial Stiffness in Arterial Hypertension
Khusanjon PulatovRepublican Specialized Scientific and Practical Medical Center of Cardiology, Tashkent, Uzbekistan
Zenodo (CERN European Organization for Nuclear Research)repository2026
ABI
Abstract
In patients with hypertension, target organ damage, including left ventricular hypertrophy and increased arterial stiffness, worsens the prognosis. A study involving 52 patients evaluated the effect of 6 months of therapy with the fixed-dose combination of telmisartan/amlodipine. A significant reduction in left ventricular myocardial mass index (by 7.6%), central arterial pressure, and pulse wave velocity was found. These data indicate a pronounced cardioprotective and vasoprotective effect of the therapy, which may contribute to an improved long-term prognosis in patients with hypertension.
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