Article

EARLY STRUCTURAL AND FUNCTIONAL CHANGES OF THE MYOCARDIUM IN PATIENTS WITH METABOLIC SYNDROME: A CLINICO-MORPHOLOGICAL ANALYSIS

Nigoraxon Ravshanbek kizi MadraximovaFergana medical institute of public health

Zenodo (CERN European Organization for Nuclear Research)repository2026en

ABI

Abstract

This study aimed to evaluate early structural and functional myocardial changes in patients with metabolic syndrome. A clinico-morphological approach was applied, including anthropometric, biochemical, and echocardiographic assessments[1,2,3]. Insulin resistance was evaluated using the HOMA-IR index. The results demonstrated early diastolic dysfunction, mitochondrial impairment, and microvascular disturbances, contributing to fibrotic changes in the myocardium. These findings highlight the importance of early diagnosis and pathogenetic treatment to prevent progression to heart failure.

Topics

Cardiovascular Function and Risk Factors Diabetes, Cardiovascular Risks, and Lipoproteins Cardiac Imaging and Diagnostics

Identifiers

DOI: 10.5281/zenodo.20056750

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