RECURRENT PREGNANCY LOSS AND INABILITY TO CARRY PREGNANCY TO TERM
Abstract
Recurrent pregnancy loss is a major reproductive health problem that affects millions of women worldwide and remains one of the most challenging conditions in obstetrics and gynecology. The present study aimed to investigate the primary clinical causes associated with the inability to maintain pregnancy and to evaluate modern diagnostic and therapeutic approaches used in the management of recurrent miscarriage. A retrospective observational study was conducted involving 120 women with a history of two or more consecutive pregnancy losses. Clinical evaluation included reproductive history analysis, hormonal assessment, ultrasonography, immunological screening, coagulation testing, and genetic consultation where indicated. The findings demonstrated that hormonal disorders, uterine structural abnormalities, autoimmune dysfunction, thrombophilic conditions, and psychological stress were among the most significant factors contributing to recurrent pregnancy failure. Women receiving individualized multidisciplinary treatment showed improved pregnancy continuation outcomes compared with patients managed using isolated symptomatic therapy. The study additionally revealed the substantial emotional burden experienced by affected women, emphasizing the importance of integrating psychological support into reproductive healthcare. Early diagnosis, comprehensive etiological assessment, and personalized management strategies remain essential for improving maternal prognosis and reducing recurrent miscarriage rates.