The role of the inflammatory process in the pathophysiological mechanisms of spermatogenesis disorders in varicocele patients. Part 3
V.S. StepanovDepartment of Endoscopic Urology and Ultrasound Diagnostic, Faculty of Continuous Medical Education of Medical Institute, Peoples’ Friendship University of Russia; SM-Clinic medical holdingM.V. FanievDepartment of Endoscopic Urology and Ultrasound Diagnostic, Faculty of Continuous Medical Education of Medical Institute, Peoples’ Friendship University of RussiaM.A. ChakiryanSM-Clinic medical holdingV.V. PapsuevDepartment of Endoscopic Urology and Ultrasound Diagnostic, Faculty of Continuous Medical Education of Medical Institute, Peoples’ Friendship University of Russia; SM-Clinic medical holdingА.A. AlekseevDepartment of Endoscopic Urology and Ultrasound Diagnostic, Faculty of Continuous Medical Education of Medical Institute, Peoples’ Friendship University of RussiaK. M. MyskovSM-Clinic medical holdingT.A. PirovDepartment of Endoscopic Urology and Ultrasound Diagnostic, Faculty of Continuous Medical Education of Medical Institute, Peoples’ Friendship University of Russia; National Medical Center of the Republic of Tajikistan “Shifobakhsh”З. А. КадыровDepartment of Endoscopic Urology and Ultrasound Diagnostic, Faculty of Continuous Medical Education of Medical Institute, Peoples’ Friendship University of Russia
Andrology and Genital Surgeryjournal2026
ABI
Abstract
Multiple evidence suggests that inflammation and oxidative stress negatively affect sperm parameters, spermatogenesis, and testicular and epididymal function, although the etiology of infertility caused by varicocele may be multifactorial. In this regard, the anti-inflammatory effect of various drugs in patients with varicocele is being studied and in the future, it may be possible to develop new treatment methods and conduct an appropriate selection of patients for whom these drugs can help. The article presents a review of the world literature on the influence of the inflammatory process on spermatogenesis in varicocele.
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