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Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

David M. EvansMedical Research Council (MRC) Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UKChris C. A. SpencerWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UKJennifer J. PointonNational Institute for Health Research Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford, UKZhan SuWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UKDavid HarveyNational Institute for Health Research Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford, UKGrazyna KochanStructural Genomics Consortium, University of Oxford, Oxford, UKUdo OppermannStructural Genomics Consortium, University of Oxford, Oxford, UKAlexander DiltheyMedical Research Council (MRC) Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UKMatti PirinenMedical Research Council (MRC) Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UKMillicent StoneUniversity of Bath, Bath, UKLouise AppletonNational Institute for Health Research Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford, UKLoukas MoutsianasDepartment of Statistics, University of Oxford, Oxford, UKStephen LeslieDepartment of Clinical Pharmacology, University of Oxford, Oxford, UKTom WordsworthNational Institute for Health Research Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford, UKTony KennaUniversity of Queensland Diamantina Institute, Princess Alexandra Hospital, Brisbane, AustraliaTugce KaraderiNational Institute for Health Research Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford, UKGethin ThomasUniversity of Queensland Diamantina Institute, Princess Alexandra Hospital, Brisbane, AustraliaMichael M. WardNational Institute of Arthritis and Musculoskeletal and Skin Diseases, US National Institutes of Health (NIH), Bethesda, Maryland, USAMichael H. WeismanDepartment of Medicine/Rheumatology, Cedars-Sinai Medical Centre, Los Angeles, California, USAClaire FarrarNational Institute for Health Research Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford, UKLinda A. BradburyUniversity of Queensland Diamantina Institute, Princess Alexandra Hospital, Brisbane, AustraliaPatrick DanoyUniversity of Queensland Diamantina Institute, Princess Alexandra Hospital, Brisbane, AustraliaRobert D. InmanUniversity of Toronto, Toronto, Ontario, CanadaWalter P. MaksymowychDepartment of Medicine, University of Alberta, Edmonton, Alberta, CanadaDafna GladmanMemorial University, St. John's, Newfoundland, CanadaProton RahmanMemorial University, St. John's, Newfoundland, CanadaAnn W MorganNational Institute for Health Research (NIHR)-Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, UKHelena Marzo-OrtegaNational Institute for Health Research (NIHR)-Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, UKPaul BownessNational Institute for Health Research Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford, UKKarl GaffneyDepartment of Rheumatology, Norfolk & Norwich University Hospital, Norfolk, UKJ. S. Hill GastonDepartment of Medicine, University of Cambridge, Addenbrookes Hospital, Cambridge, UKMalcolm SmithRepatriation General Hospital, Adelaide, AustraliaJácome Bruges‐ArmasGenetics and Arthritis Research Group, Institute for Molecular and Cell Biology (IBMC), University of Porto, Porto, PortugalAna Rita CoutoServio Especializado De Epidemiologia E Biologia Molecular, Hospital de Santo Esprito, Angra do Herosmo, Terceira, The Azores, PortugalRosa SorrentinoDepartment of Biology and Biotechnology 'Charles Darwin', Sapienza University of Rome, Rome, ItalyFabiana PaladiniDepartment of Biology and Biotechnology 'Charles Darwin', Sapienza University of Rome, Rome, ItalyManuel A. R. FerreiraQueensland Institute of Medical Research, Brisbane, AustraliaHuji XuDepartment of Rheumatology and Immunology, Shanghai Changzheng Hospital, The Second Military Medical University Hospital, Shanghai, ChinaYu LiuDepartment of Rheumatology and Immunology, Shanghai Changzheng Hospital, The Second Military Medical University Hospital, Shanghai, ChinaLei JiangDepartment of Rheumatology and Immunology, Shanghai Changzheng Hospital, The Second Military Medical University Hospital, Shanghai, ChinaCarlos López‐LarreaDepartment of Immunology, Hospital Universitario Central de Asturias, Oviedo, SpainRoberto Díaz‐PeñaDepartment of Immunology, Hospital Universitario Central de Asturias, Oviedo, SpainAntonio López‐VázquezDepartment of Immunology, Hospital Universitario Central de Asturias, Oviedo, SpainTetyana ZayatsMedical Research Council (MRC) Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UKGavin BandWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UKCéline BellenguezUniversity of OxfordHannah BlackburnDepartment of Immunology, Hospital Universitario Central de Asturias, Oviedo, SpainJenefer M. BlackwellGenetics and Infection Laboratory, Cambridge Institute of Medical Research, Addenbrooke's Hospital, Cambridge, UKElvira BramonWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKSuzannah J. BumpsteadWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKJuan Pablo CasasDepartment of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UKAiden CorvinNeuropsychiatric Genetics Research Group, Institute of Molecular Medicine, Trinity College Dublin, Dublin, IrelandNicholas CraddockDepartment of Psychological Medicine, School of Medicine, Cardiff University, Cardiff, WalesPanos DeloukasWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKSerge DronovWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKAudrey DuncansonMolecular and Physiological Sciences, The Wellcome Trust, London, UKSarah EdkinsWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKColin FreemanWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UKMatthew GillmanWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKEmma GrayWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKRhian GwilliamWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKNaomi HammondWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKSarah HuntWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKJanusz JankowskiAlagurevathi JayakumarWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKCordelia LangfordWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKJennifer LiddleWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKHugh S. MarkusClinical Neurosciences, St. George's University of London, London, UKChristopher G. MathewDivision of Genetics and Molecular Medicine, King's College London, London, UKOwen T McCannWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKMark I. McCarthyOxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford, UK. 35 Biomedical Research Centre, Ninewells Hospital and Medical School, Dundee, UK. 36 Social, Genetic and Developmental Psychiatry Centre, King's College London Institute of Psychiatry, Denmark Hill, London, UK. 37 Department of Cardiovascular Science, University of Leicester, Glenfield General Hospital, Leicester, UK. 38 University of Cambridge, Department of Clinical Neurosciences, Addenbrooke's Hospital, Cambridge, UK. 39 Glaucoma Research Unit, Moorfields Eye Hospital NHS Foundation Trust, London, UK. 40 Department of Genetics, University College London Institute of Ophthalmology, London, UK. 41 Department of Molecular Neuroscience, Institute of Neurology, Queen Square, London, UK. 42 Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston, Houston, Texas, USAColin N A PalmerBiomedical Research Centre, Ninewells Hospital and Medical School, Dundee, UKLeena PeltonenWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKRobert PlominSocial, Genetic and Developmental Psychiatry Centre, King's College London Institute of Psychiatry, Denmark Hill, London, UKSimon PotterWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKAnna RautanenWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKRathi RavindrarajahWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKMichelle RickettsWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKNilesh J. SamaniDepartment of Cardiovascular Science, University of Leicester, Glenfield General Hospital, Leicester, UKStephen SawcerDepartment of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Cambridge, UKAmy StrangeWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UKRichard C. TrembathDivision of Genetics and Molecular Medicine, King's College London, London, UKAnanth C. ViswanathanGlaucoma Research Unit, Moorfields Eye Hospital NHS Foundation Trust, London, UKMatthew WallerWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKPaul A. WestonWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKPamela WhittakerWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKSara WidaaWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UKNicholas WoodDepartment of Molecular Neuroscience, Institute of Neurology, Queen Square, London, UKGil McVeanWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UKJohn D. ReveilleRheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston, Houston, Texas, USAB P WordsworthNational Institute for Health Research Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford, UKMatthew A. BrownUniversity of Queensland Diamantina Institute, Princess Alexandra Hospital, Brisbane, AustraliaPeter DonnellyWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
2011en
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Cited by 20 references