Studies on Nepalese crude drugs. V. On the flavonoid constituents of the root of Scutellaria discolor COLEBR.
Tsuyoshi TomimoriResearch Institute for Wakan-Yaku, Toyama Medical and Pharmaceutical University, School of Pharmacy, Hokuriku University, School of Pharmacy, Hokuriku University, School of Pharmacy, Hokuriku University, School of Pharmacy, Hokuriku UniversityYukinori MiyaichiResearch Institute for Wakan-Yaku, Toyama Medical and Pharmaceutical University, School of Pharmacy, Hokuriku University, School of Pharmacy, Hokuriku University, School of Pharmacy, Hokuriku University, School of Pharmacy, Hokuriku UniversityYoshitaka ImotoResearch Institute for Wakan-Yaku, Toyama Medical and Pharmaceutical University, School of Pharmacy, Hokuriku University, School of Pharmacy, Hokuriku University, School of Pharmacy, Hokuriku University, School of Pharmacy, Hokuriku UniversityHaruhisa KizuResearch Institute for Wakan-Yaku, Toyama Medical and Pharmaceutical University, School of Pharmacy, Hokuriku University, School of Pharmacy, Hokuriku University, School of Pharmacy, Hokuriku University, School of Pharmacy, Hokuriku UniversityTsuneo NambaResearch Institute for Wakan-Yaku, Toyama Medical and Pharmaceutical University, School of Pharmacy, Hokuriku University, School of Pharmacy, Hokuriku University, School of Pharmacy, Hokuriku University, School of Pharmacy, Hokuriku University
1985en
ABI
Abstract
Four new flavanones (I-IV) and a new chalcone (V) were isolated from the root of Scutellaria discolor COLEBR., together with wogonin, norwogonin, 5, 7, 2'-trihydroxy-8-methoxyflavone, 5, 7-dihydroxy-8, 2'-dimethoxyflavone and wogonin 7-O-glucuronide. The structures of I-V were shown to be 2 (S)-5, 7-dihydroxy-8, 2'-dimethoxyflavanone, 2 (S)-7-hydroxy-5, 8, 2'-trimethoxyflavanone, (±)-5, 2'-dihydroxy-7, 8, 6'-trimethoxyflavanone, (±)-5, 2'-dihydroxy-6, 7, 6'-trimethoxyflavanone and 2', 4'-dihydroxy-2, 3', 6'-trimethoxychalcone, respectively, based on spectral data and simple chemical modifications.
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