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Mussel-Inspired Surface Chemistry for Multifunctional Coatings

Haeshin LeeBiomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USAShara M. DellatoreBiomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USAWilliam M. MillerBiomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USAPhillip B. MessersmithBiomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA
2007en
ABI

Abstract

We report a method to form multifunctional polymer coatings through simple dip-coating of objects in an aqueous solution of dopamine. Inspired by the composition of adhesive proteins in mussels, we used dopamine self-polymerization to form thin, surface-adherent polydopamine films onto a wide range of inorganic and organic materials, including noble metals, oxides, polymers, semiconductors, and ceramics. Secondary reactions can be used to create a variety of ad-layers, including self-assembled monolayers through deposition of long-chain molecular building blocks, metal films by electroless metallization, and bioinert and bioactive surfaces via grafting of macromolecules.

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Cited by 20 references