Synthesis of tertiary propargylamines <i>via</i> a rationally designed multicomponent reaction of primary amines, formaldehyde, arylboronic acids and alkynes
Jiayi WangShanghai Key Laboratory of Catalysis Technology for PolyolefinsQiaoying ShenEast China University of Science and TechnologyPinzhen LiEast China University of Science and TechnologyYanqing PengEast China University of Science and TechnologyGonghua SongEast China University of Science and Technology
2014en
ABI
Abstract
A novel approach for the synthesis of tertiary propargylamines is achieved through a Cu(OAc)2-catalyzed multicomponent reaction of primary amines, formaldehyde, arylboronic acids and alkynes, where a combination of PBM and A(3)-coupling reactions is involved in this new multicomponent reaction.
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